Immunoaffinity CE for Proteomics Studies.

Immunoaffinity CE for

Evaluation of multiprotein immunoaffinity subtraction for plasma proteomics and candidate biomarker discovery using mass spectrometry.

Strategies for removal of high abundance proteins have been increasingly utilized in proteomic studies of serum/plasma and other body fluids to enhance the detection of low abundance proteins and achieve broader proteome coverage; however, both the reproducibility and specificity of the high abundance protein depletion process still represent common concerns. Here we report a detailed evaluatio...

Developments in Interfacing Designs for CE–MS: Towards Enabling Tools for Proteomics and Metabolomics

Capillary electrophoresis–electrospray ionization-mass spectrometry (CE-ESI-MS) has emerged as a powerful tool for the analysis of charged compounds in biological samples [1–3]. CE–MS can be used for the characterization of a wide variety of analytes, e.g., metabolites, peptides, glycans and intact proteins [4–6]. So far, the co-axial sheath–liquid interface has been primarily used for the coup...

Nioboaeschynite-(Ce), Ce(NbTi)O6

Nioboaeschynite-(Ce), ideally Ce(NbTi)O(6) [cerium(III) niobium(V) titanium(IV) hexa-oxide; refined formula of the natural sample is Ca(0.25)Ce(0.79)(Nb(1.14)Ti(0.86))O(6)], belongs to the aeschynite mineral group which is characterized by the general formula AB(2)(O,OH)(6), where eight-coordinated A is a rare earth element, Ca, Th or Fe, and six-coordinated B is Ti, Nb, Ta or W. The general st...

Schistosomes--proteomics studies for potential novel vaccines and drug targets.

Schistosomiasis is a major health problem and, despite decades of research, only one effective drug, Praziquantel is currently available. Recent expansion of sequence databases on Schistosoma mansoni and S. japonicum has permitted a wealth of novel proteomic studies on several aspects of the organization and development of the parasite in the human host. This unprecedented accumulation of molec...